Table 2 Multivariable models for death prediction.
Variables at baseline | Model A (2014 risk score) Harrell’s C: 0.69 | Model B (2024 update) Harrell’s C: 0.75 | ||
|---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | |
Age | ||||
<57 years | 1.00 (Ref.) | 1.00 (Ref.) | ||
57-66 | 1.80 (1.12-2.86) | 0.015 | 1.74 (1.06-2.85) | 0.029 |
≥67 | 4.03 (2.69-6.02) | <0.001 | 3.32 (2.13-5.17) | <0.001 |
WBC ≥ 15 ×109/L | 1.65 (1.15-2.38) | 0.007 | 1.18 (0.78-1.79) | 0.43 |
NLR ≥ 5 | - | - | 1.84 (1.30-2.59) | 0.001 |
Previous venous thrombosis | 1.57 (1.08-2.29) | 0.018 | 1.53 (1.01-2.33) | 0.045 |
Cardiovascular risk factors | ||||
Hypertension | - | - | 0.98 (0.70-1.38) | 0.92 |
Hypercholesterolemia | - | - | 0.69 (0.25-1.90) | 0.48 |
Diabetes mellitus | - | - | 2.26 (1.41-3.61) | 0.001 |
Congestive heart failure | - | - | 2.75 (1.84-4.10) | <0.001 |
Smoke | ||||
No smoke | - | - | 1.00 (Ref.) | |
Current smokers | - | - | 2.47 (1.53-3.97) | <0.001 |
Former smokers | - | - | 1.32 (0.88-1.97) | 0.18 |
