Fig. 1: Kaplan-Meier analysis of overall survival (OS), leukemia-free survival (LFS) and the impact of genomic factors on OS and LFS in 1225 patients with primary myelodysplastic neoplasm (MDS) in Asia.

A Overall survival of primary MDS in Asia; B Adverse prognostic impact of monosomy 7 (-7) on overall survival in primary MDS in Asia; C Adverse prognostic impact of del(5q) on overall survival in primary MDS in Asia; D Adverse prognostic impact of GNAS mutations on overall survival in primary MDS in Asia; E Adverse prognostic impact of TP53 mutations on overall survival in primary MDS in Asia; F Leukemia-free survival of primary MDS in Asia; G Adverse prognostic impact of trisomy 19 (+19) on leukemia-free survival in primary MDS in Asia; H Adverse prognostic impact of 5q deletion [del(5q)] on leukemia-free survival in primary MDS in Asia; I Adverse prognostic impact of monosomy 7 (-7) on leukemia-free survival in primary MDS in Asia; J Adverse prognostic impact of GNAS mutations on leukemia-free survival in primary MDS in Asia; K Adverse prognostic impact of PTPN11 mutations on leukemia-free survival in primary MDS in Asia; L Adverse prognostic impact of TP53 mutations on leukemia-free survival in primary MDS in Asia. All P-values were obtained using log-rank test. The genomic factors shown were significant on multivariable analysis (see Table 2).