Table 3 Factors associated with outcomes in Cox regression analysis.

From: Haploidentical hematopoietic stem cell transplantation for hematologic malignancies: a novel conditioning regimen with anti-T lymphocyte immunoglobulin instead of anti-thymocyte globulin for in vivo T cell depletion

Factors

OS

RFS

CIR

NRM

 

Univariate (p,(HR,95% CI))

Multivariate (p,(HR,95% CI))

Univariate (p,(HR,95% CI))

Multivariate (p,(HR,95% CI))

Univariate (p,(HR,95% CI))

Multivariate (p,(HR,95% CI))

Univariate (p,(HR,95% CI))

Multivariate (p,(HR,95% CI))

Age of recipients

0.056

0.067

0.035(1.018,1.001–1.035)

0.409

0.148

0.545

0.081

0.049(1.047,1.000–1.096)

Donor-recipient relationships

0.534

0.590

0.291

0.176

0.611

0.408

0.364

0.558

Positive MRD before HSCT

0.0007(5.136,2.954–8.930)

0.0003(4.114,2.274–7.444)

0.0002(7.237,4.44–11.80)

0.0002(7.535,4.406–12.885)

0.006(7.481,4.593–12.186)

0.0006(6.619,4.174–11.461)

0.244

0.925

TNC in graft

0.208

0.242

0.155

0.197

0.135

0.316

0.878

0.752

CD34 in graft

0.540

0.955

0.300

0.672

0.271

0.589

0.950

0.789

II–IV aGVHD

0.003(2.185,1.294–3.690)

0.518

0.019(1.745,1.096–2.778)

0.393

0.007(1.900,1.193–3.025)

0.291

0.001(28.105,3.676–214.870)

0.254

III–IV aGVHD

0.007(2.585,1.304–5.126)

0.633

0.268

0.539

0.192

0.784

0.0009(8.299,2.876–23.947)

0.247

cGVHD

0.005(2.135,1.264–3.606)

0.987

0.026(1.692,1.064–2.690)

0.678

0.012(1.809,1.138–2.876)

0.833

0.002(25.452,3.329–194.584)

0.728

  1. OS over survival, RFS relapse-free survival, CIR cumulative incidence of relapse, NRM non-relapse mortality, MRD minimal residence disease, HSCT hematopoietic stem cell transplantation, TNC total nucleated cells, aGVHD acute graft-versus-host disease, cGVHD chronic graft-versus-host disease.
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