Table 2 Univariable analysis of transplant outcomes according to number of induction cycles.

From: Impact of pre-transplant induction cycles on post-transplant outcomes in patients with ALL: a study from the ALWP EBMT

Outcome

1

2

≥ 3

Myeloid engraftment, CI at 30 days (%)

96 (95–96)

95 (92–97)

95 (88–97)

Platelet engraftment, CI at 60 days (%)

94 (93–95)

93 (89–95)

93 (86–97)

aGVHD grades II-IV, CI at 180 days (%)

36 (34–39)

31 (26–36)

36 (27–45)

aGVHD grades III-IV, CI at 180 days (%)

13 (11–14)

10 (7–14)

12 (6–19)

Overall cGVHD, 2-year CI (%)

41 (38–43)

40 (34–46)

42 (31–52)

Extensive cGVHD, 2-year CI (%)

19 (17–21)

17 (12–22)

20 (12–29)

NRM, 2-year CI (%)

17 (15–19)

18 (14–23)

16 (9–24)

RI, 2-year CI (%)

23 (21–25)

31 (26–37)

32 (23–42)

LFS, 2-year CI (%)

60 (57–62)

51 (45–57)

52 (41–62)

OS, 2-year CI (%)

68 (66–70)

61 (54–66)

60 (49–70)

GRFS, 2-year CI (%)

41 (39–44)

36 (30–42)

36 (26–46)

  1. aGVHD acute graft-versus-host-disease, cGVHD chronic graft-versus-host-disease, NRM non-relapse mortality, RI relapse incidence, LFS leukemia-free survival, OS overall survival, GRFS GVHD-free, relapse-free survival.