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Long-term survival in patients with Philadelphia-chromosome-positive acute lymphoblastic leukemia who relapse after allogeneic hematopoietic stem cell transplantation: a single-center experience

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Fig. 1: Overall survival after relapse in the total cohort, in the CR1 and > CR1 group and in different type of relapse.

Data availability

The datasets analyzed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

This work was supported by the National Key Research and Development Program of China (No. 2022YFA1103300), Major Program of the National Natural Science Foundation of China (No. 82293630), Beijing Municipal Science & Technology Commission (No. Z211100002921071), and Peking University Medicine Fund for world’s leading discipline or discipline cluster development (No.71003Y3035). We would like to thank Editage (www.editage.com) for language editing.

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Contributions

HC designed the study, interpreted the data, and wrote the manuscript; L-PX, X-HZ, YW, Y-HC, Y-FC, YC, X-DM, Y-QS, Y-YZ, C-HY, WH, Y-JC conducted the research and contributed to writing the manuscript; Y-ZQ performed BCR-ABL RQ-PCR, direct sequencing for BCR-ABL kinase domain mutation assays; X-JH was the principal investigator, designed the study, interpreted the data, and wrote the manuscript. All the authors have read and approved the final manuscript.

Corresponding author

Correspondence to Xiao-Jun Huang.

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The authors declare no competing interests.

Ethics approval and consent to participate

The study was reviewed and approved by the Ethics Committee of Peking University People’s Hospital and was conducted in accordance with the Declaration of Helsinki. Patients or their legal guardians had provided written informed consent for the data collection and any subsequent analysis of data before the transplantation procedure.

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Chen, H., Xu, LP., Zhang, XH. et al. Long-term survival in patients with Philadelphia-chromosome-positive acute lymphoblastic leukemia who relapse after allogeneic hematopoietic stem cell transplantation: a single-center experience. Bone Marrow Transplant (2025). https://doi.org/10.1038/s41409-025-02698-9

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