Table 6 Remimazolam dosage, VAS-T, Ramsay and PADSS scores by phase

From: Remimazolam besylate in intravenous conscious sedation for dental treatment: a prospective cohort study

 

Remimazolam (%)

VAS-T (mean ± SD; min-median-max)

Ramsay score (%)

PADSS score (mean ± SD; min-median-max)

Pre-operative phase

/

3.63 ± 2.04; 0-4-9

/

/

Induction phase

Induction I

2.5 mg = 28.0

5.0 mg = 33.0

7.0 mg = 40.0

7.78 ± 1.31; 4-8-10

1 = 16.0

2 = 57.0

3 = 21.0

4 = 5.0

5 = 1.0

6 = 0

/

Induction II

1.25 mg = 5.0

2.5 mg = 95.0

8.07 ± 0.81; 6-8-10

1 = 14.0

2 = 56.0

3 = 30.0

4 = 0

5 = 0

6 = 0

/

Induction III

1.25 mg = 0

2.5 mg = 100.0

8.00; 8-8-8

1 = 33.0

2 = 67.0

3 = 0

4 = 0

5 = 0

6 = 0

/

Induction IV

1.25 mg = 0

2.5 mg = 100.0

/

1 = 67.0

2 = 33.0

3 = 0

4 = 0

5 = 0

6 = 0

/

Induction V

1.25 mg = 0

2.5 mg = 100.0

/

1 = 0

2 = 100.0

3 = 0

4 = 0

5 = 0

6 = 0

/

Maintenance phase

Maintenance I

1.25 mg = 6.0

2.5 mg = 94.0

5 mg = 0

/

1 = 3.0

2 = 74.0

3 = 22.0

4 = 1.0

5 = 0

6 = 0

/

Maintenance II

1.25 mg = 8.0

2.5 mg = 92.0

5 mg = 0

/

1 = 2.0

2 = 73.0

3 = 22.0

4 = 2.0

5 = 0

6 = 0

/

Maintenance III

1.25 mg = 6.0

2.5 mg = 94.0

5 mg = 0

/

1 = 1.0

2 = 79.0

3 = 18.0

4 = 1.0

5 = 0

6 = 0

/

Maintenance IV

1.25 mg = 8.0

2.5 mg = 92.0

5 mg = 0

/

1 = 2.0

2 = 83.0

3 = 15.0

4 = 0

5 = 0

6 = 0

/

Maintenance V

1.25 mg = 15.0

2.5 mg = 85.0

5 mg = 0

/

1 = 4.0

2 = 85.0

3 = 12.0

4 = 0

5 = 0

6 = 0

/

Maintenance VI

1.25 mg = 19.0

2.5 mg =75.0

5 mg = 6.0

/

1 = 0

2 = 88.0

3 = 13.0

4 = 0

5 = 0

6 = 0

/

Maintenance VII

1.25 mg = 20.0

2.5 mg = 80.0

5 mg = 0

/

1 = 0

2 = 100.0

3 = 0

4 = 0

5 = 0

6 = 0

/

Maintenance VIII

1.25 mg = 25.0

2.5 mg = 75.0

5 mg = 0

/

1 = 0

2 = 100.0

3 = 0

4 = 0

5 = 0

6 = 0

/

Maintenance IX

1.25 mg = 20.0

2.5 mg = 80.0

5 mg = 0

/

1 = 0

2 = 100.0

3 = 0

4 = 0

5 = 0

6 = 0

/

Maintenance X

1.25 mg = 0

2.5 mg = 100.0

5 mg = 0

/

1 = 0

2 = 100.0

3 = 0

4 = 0

5 = 0

6 = 0

/

End of procedure

/

9.34 ± 1.20; 5-10-10

1 = 2.0

2 = 84.0

3 = 12.0

4 = 2.0

5 = 0

6 = 0

/

Discharge

/

/

/

9.96 ± 0.24; 8-10-10

Key:

Max = maximum; Min = minimum; PADDS = Post Anaesthesia Discharge Scoring System; SD = standard deviation; VAS-T = Visual Analogue Scale for Tranquility.

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