Fig. 3: Survival analysis of pan-cancer from TCGA.
From: Synthetic viability induces resistance to immune checkpoint inhibitors in cancer cells
a The overlapping of survival related SV gene pairs across various cancer types. Kaplan-Meier plots of patients with low and high SV-score (cutoff was median of scores) in BRCA (b), LGG (c), HNSC (d), and SKCM (e) cohorts. The P values were computed by log-rank test. Multivariate Cox regression analysis of the SV-score, age, and stage in BRCA (f), LGG (g), HNSC (h), and SKCM (i) cohorts. j AUCs for SV gene pairs performance in predicting drug response. k Prediction of SV gene pairs in terms of survival: The x-axis displays the hazard ratio of patients result from multivariate Cox regression analysis of SV gene pairs. For P value, * denotes P < 0.05, ** denotes P < 0.01, and *** denotes P < 0.001.
