Fig. 2: Subchromosomal alterations and co-occurrence patterns in the cohort. | British Journal of Cancer

Fig. 2: Subchromosomal alterations and co-occurrence patterns in the cohort.

From: Benchmarking standard-of-care and emerging genomic approaches to enhance diagnosis in pediatric acute lymphoblastic leukemia

Fig. 2

a Chromosomal ideogram illustrating subchromosomal gains (green circles) and losses (orange triangles) detected across the cohort. The colour gradient represents the frequency of alterations, ranging from none (blue) to high (red). b Heatmap displaying significant co-occurrence and mutual exclusivity relationships among genomic alterations. The intensity of the colour represents the –log10(p-value), with darker shades indicating stronger statistical significance. Significant interactions are marked with * (p < 0.01) and • (p < 0.05).

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