Table 1 Clinical features of twelve KRASG12C patient LUAD tumours, their derived xenografts and downstream organoids
Model (PHLC ID) | Stage | Sex | TP53 Mutation (PDX) | Gene Expression Subtype (PDX) | Long-Term Organoid From PDX |
|---|---|---|---|---|---|
82 | IB | F | M237I Q317* | TRU | Yes |
151 | IB | F | - | PP | Unsuccessful |
191 | IV | F | R181P | PP | Unsuccessful |
194 | IB | M | - | PI | Yes |
207 | IIA | F | R110L | TRU | Yes |
237 | IIB | F | - | PP | Unsuccessful |
239 | IA | M | - | PP | Yes |
256 | IB | M | Deep Del | PP | Unsuccessful |
277 | IIB | M | R337P | PP | Unsuccessful |
334 | IB | M | - | PP | Unsuccessful |
344 | IA | M | G199V | TRU | Yes |
362 | IIA | M | R158L | PI | Yes |
