Fig. 1: Characterization and prognostic impact of TLS in ESCC. | Cancer Gene Therapy

Fig. 1: Characterization and prognostic impact of TLS in ESCC.

From: Characterization of tertiary lymphoid structure identifies competitive binding of CD40 and STING with TRAF2 driving IRF4-mediated B cell activation in esophageal squamous cell carcinoma

Fig. 1

A Representative image of TLS+ and TLS- detected in formalin-fixed paraffin-embedded tumor sections by haematoxylin and eosin (H&E) staining and images of TLS+ detected by immunohistochemistry staining showing CD3 + T cell zones and CD20 + B cell zones (scale bar = 100 μm). Kaplan–Meier curves for RFS (B) and OS (C) in ESCC patients based on the presence of TLS. TLS tertiary lymphoid structures, ESCC esophageal squamous cell carcinoma, RFS recurrence-free survival, OS overall survival.

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