Fig. 2: Identification of TLS-related immunophenotypes and DEGs of ESCC. | Cancer Gene Therapy

Fig. 2: Identification of TLS-related immunophenotypes and DEGs of ESCC.

From: Characterization of tertiary lymphoid structure identifies competitive binding of CD40 and STING with TRAF2 driving IRF4-mediated B cell activation in esophageal squamous cell carcinoma

Fig. 2

A Immune infiltration patterns of ESCC stratified by the presence of TLS in the GEO dataset GSE53625. B Immune infiltration patterns of ESCC stratified by the presence of TLS in 41 surgical specimens from the internal cohort. C Impact of the intersecting gene IRF4 on the prognosis of ESCC. D GO enrichment analysis of the intersecting genes. ESCC esophageal squamous cell carcinoma, DEGs differentially expressed genes, TLS tertiary lymphoid structures, IRF4 interferon regulatory factor 4, GO gene ontology.

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