Fig. 1: GLUL plays an important role in the osteogenic differentiation of BMSCs and the progression of SOP. | Cell Death & Differentiation

Fig. 1: GLUL plays an important role in the osteogenic differentiation of BMSCs and the progression of SOP.

From: GLUL mediates FOXO3 O-GlcNAcylation to regulate the osteogenic differentiation of BMSCs and senile osteoporosis

Fig. 1

A Heatmap of the metabolic and transcriptional changes that occur during the osteogenic differentiation of human mesenchymal stem cells according to the GSE191136 dataset. B Western blotting analysis of GLUL expression during the osteogenic differentiation of BMSCs. C Immunohistochemical staining analysis of GLUL expression in mouse femur sections at different times after birth. D Heatmap of the effects of SOP on human mesenchymal stem cells according to the GSE35956 dataset. E Immunohistochemical staining analysis of GLUL expression in femur sections from young and old samp6 mice (n = 3). F Quantification of GLUL expression in bone samples from patients with SOP. G Western blotting analysis of GLUL expression in BMSCs from patients in the SOP group (n  = 6) and the control group (n = 7). ** P < 0.01 vs. other groups; *P < 0.05 vs. other groups.

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