Fig. 5: SREBF1 was a common highly expressed gene in the IMPC clusters of four samples. | Cell Death & Disease

Fig. 5: SREBF1 was a common highly expressed gene in the IMPC clusters of four samples.

From: Spatial transcriptomics reveals gene expression characteristics in invasive micropapillary carcinoma of the breast

Fig. 5

A The Venn plot showed that SREBF1 was a common high expression gene in all IMPC clusters of the 4 samples. B SREBF1 was highly expressed in IMPC clusters of each sample in spatial plots. C Boxplot of SREBF1 expression level in IMPC clusters versus IDC-NOS clusters. Bar represents median, and boxplot represents quartiles; scale in log10(RPM). Student’s t-test for comparison between two groups in each sample. The difference was significant in sample 1 (P < 2e-16), sample 3 (P = 2.1e-08) and sample 4 (P < 2e-16). D The correlation analysis between SREBF1 and FASN using TCGA database. The Pearson correlation coefficient was used, two-sided. P < 0.05 was considered to indicate statistical significance. E SREBF1 was more highly expressed in IMPC tumor tissues using RT-qPCR. Bar represents median, and boxplot represents quartiles. Student’s t-test for comparison. The two groups were significantly different (P = 0.013).

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