Fig. 6: Clinical outcomes associated with the expression of the SREBF1 and FASN proteins in 82 patients with IMPC and 80 with IDC-NOS.

A Images of immunohistochemical staining for SREBF1 and FASN in patients with IMPC (n = 82) and IDC-NOS (n = 80). The upper panel shows high expression of SREBF1 and FASN in patients with IMPC; the lower panel shows low expression of the SREBF1 and FASN proteins in patients with IDC-NOS, x400 magnification. B The association of SREBF1 and FASN protein expression with disease-free survival (DFS) and overall survival (OS). The light panel shows SREBF1, and the right panel shows FASN, with patients with IMPC stratified by high and low protein expression. Log-rank test, two-sided. The P values for DFS of SREBF1 and FASN were 0.022, and 0.009, respectively; the P values for OS of SREBF1 and FASN were 0.044 and 0.015, respectively. P < 0.05 was considered to indicate statistical significance.