Fig. 4: Advanced anti-cancer strategies which can be combined with CSC mTOR-targeting therapies. | Cell Death & Disease

Fig. 4: Advanced anti-cancer strategies which can be combined with CSC mTOR-targeting therapies.

From: Targeted therapy of cancer stem cells: inhibition of mTOR in pre-clinical and clinical research

Fig. 4

For enhanced anti-cancer treatment, mTOR-targeting strategy can be combined with DNA/RNA-targeting anti-cancer therapies (A), mTOR partner inhibition (B), TME-targeting immunotherapy (C), anti-tumor immunity activation through M1 macrophage polarization or T cell activation (D), and advanced drug delivery system using virus, nanoparticles, or nanovesicles (E).

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