Fig. 6: E2F1, as a transcription factor, predictably regulates the expression of HSPB6 and PROSER3.
From: 8-Br-cGMP activates HSPB6 and increases the antineoplastic activity of quinidine in prostate cancer
A The process of screening transcription factor E2F1. B The ChIP-seq results showed the binding of E2F1 to the HSPB6 promoter region. C Schematic diagram of the HSPB6 promoter region. D The binding site of E2F1 in the HSPB6 promoter region. E, F Correlation analysis of E2F1 with HSPB6 (E) and PROSER3 (F) from the TCGA database. G, H Correlation analysis of E2F1 with HSPB6 (G) and PROSER3 (H) from the CCLE database.
