Fig. 5: Selective ablation of MIAT in cardiomyocytes suppresses cardiac fibrosis after chronic myocardial infarction. | Cell Death Discovery

Fig. 5: Selective ablation of MIAT in cardiomyocytes suppresses cardiac fibrosis after chronic myocardial infarction.

From: Cardiomyocyte-restricted MIAT deletion is sufficient to protect against murine myocardial infarction

Fig. 5

Representative Masson’s Trichrome staining (A–B) in heart sections from the four experimental groups at 4 weeks post-MI and fibrosis quantification (C). Fibrosis histology images from whole heart sections (A, Scale bars: 1 mm) and zoomed in images of the peri-ischemic border area (B, Scale bars: 100 ÎŒm). N = 6–7 per group. Data are presented as the mean ± SEM. Two-way ANOVA with Tukey’s multiple comparison test. *P < 0.05 or ***P < 0.001 vs. sham of same genotype; ##P < 0.00 vs. MI MIATfl/fl.

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