Table 1 Small molecules and their targets in prostate cancer.
From: Emerging implications of N6-methyladenosine in prostate cancer progression and treatment
Small molecules | Target | Experiment model | Reference |
|---|---|---|---|
β-elemive | METTL3 | Patients with Nonmetastatic Prostate Cancer | [169] |
STM2457 | METTL3 | PC3,22RV1,DU145 | [126] |
IGF2BP2 | MYC | Patients with prostate cancer | |
UZH2 | METTL3 | PC-3 | [133] |
curcumin | TGF-β | SCID mice implanted with C4-2B | [134] |
HDAC4 | LNCaP | [135] | |
AR | 22Rv1 | [136] | |
MIR-141 | |||
MIR-183 | |||
baicalin | FOXM1 | LNCaP PC3 | [140] |
NF-κB p65 | In situ PCa stem cells (PCSCs) injected BALB/c nude mice | [141] |
