Table 1 Regulatory mechanisms of noncoding RNAs in PCD of breast cancer.
ncRNAs | Expression | Mechanism | Role in PCD | Reference(s) |
|---|---|---|---|---|
circ_0022587 | Down | Target miR-335-5p /Phosphoglycerate Kinase 1 Pathway | Promote apoptosis | [162] |
LURAP1L-AS1 | Up | Modulate oncogenes including EZH2, MCL1, and KRAS, | Promote apoptosis | [163] |
miR-223-3p | Up | Target and downregulate KIF4A | Promote apoptosis | [164] |
lncRNA AC112721.1 | Down | Bind to THBS1 and regulate miR-491-5p/C2CD2L axis | Inhibit apoptosis | [165] |
hsa-miR-214-3p | Up | Downregulate B7H3 | Promote apoptosis | [166] |
miR-484 | Up | Suppress apoptosis in BC cells | Inhibit apoptosis | [167] |
miR-454-3p | Up | Target ACSL4 | Inhibit ferroptosis | [168] |
miR-128-3p | Up | Suppress SP1 and CD98hc | Promote ferroptosis | [169] |
lncRNA PTPRG-AS1 | Up | Inhibit ferroptosis in breast cancer via miR-376c-3p/SLC7A11 axis | Inhibit ferroptosis | [170] |
circ_0000643 | Up | Enhance the expression of SLC7A11 | Inhibit ferroptosis | [171] |
LINC00460 | Up | Regulate LINC00460/miR-320a/MAL2 axis | Inhibit ferroptosis | [172] |
LINC01614 | Up | Upregulate SLC31A1 | Promote cuproptosis | [103] |
miR-335 | Down | SOD2 overexpression | Promote pyroptosis | [173] |
Circ_0022382 | Up | Activate PI3K/AKT/mTOR signalling pathway and SLC7A11 | Promote disulfidptosis | [174] |
miR-141-3p | Up | Target RaAB10 | Inhibit autophagy | [175] |
miR-216b | Down | Target HK2 | Promote autophagy | [175] |
