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Acknowledgements
This work was supported by the National Key R&D Program of China (2020YFA0710700), the National Natural Science Foundation of China (52025036, 51961145109), the Fundamental Research Fund for the Central Universities (WK9100000014, WK2480000006, and WK9110000061), and the project of collaborative innovation for colleges of Anhui province (GXXT-2021-070). This work was partially carried out at the USTC Center for Micro and Nanoscale Research and Fabrication. We thank Jia Wu, Jun Liu and Hao Tang from Wuhan Institute of Virology for managing of BSL-3 facility, where all the authentic SARS-CoV-2 experiments were conducted. We also thank National Virus Resource Center for providing the Omicron variant (CCPM-B-V-049-2112-18). We thank Weiheng Chen from the Animal Facility of USTC, where the mice, hamsters and macaques were vaccinated. We thank the Joint Laboratory of Innovation in Life Sciences University of Science and Technology of China (USTC) and Changchun Zhuoyi Biological Co. Ltd.
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C.W., N.-N.X., Y.-C.W., and S.C. supervised the project. Yi W., Y.-Q.S., N.-M.W., Y.-C.W., and S.C. conceived the experiments. Yi W., Y.-Q.S., N.-M.W., X.-H.Z., S.-H.C., C.Y., J.-H.Z., Yan W., D.C., L.W. conducted the experiments and analyzed the data. Yi W., Y.-Q.S., N.-M.W., N.-N.X., and Y.-C.W. wrote and revised the manuscript. C.W., H.-J.Z., and S.C. revised the manuscript. All authors read and approved the manuscript.
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N.-N.X., Y.-C.W. are co-inventors on pending patent applications related to the Omicron mRNA vaccine. The other authors declare no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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Wu, Y., Shen, Y., Wu, N. et al. Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates. Cell Res 32, 949–952 (2022). https://doi.org/10.1038/s41422-022-00706-x
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DOI: https://doi.org/10.1038/s41422-022-00706-x
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