Fig. 3: High expression of neuroendocrine (NE) markers in a small subset of lung adenocarcinoma (LUAD) and prostate adenocarcinoma (PRAD) clinical specimens.
From: Lineage plasticity and histological transformation: tumor histology as a spectrum
a–d mRNA expression levels for key NE markers CHGA, INSM1, NCAM1 and SYP in different LUAD (a, b) and PRAD (c, d) cohorts, including The Cancer Genome Atlas251 (TCGA, n = 566) (a, c), OncoSG26 (n = 305) (b) and SU2C/PCF Dream Team47 (n = 444) (d). Each blue dot represents a sample. Plots represent expression values per sample, as pre-processed and normalized in the particular study of interest. Expression values are shown to illustrate interpatient heterogeneity and a subset of tumors exhibiting differentially higher expression. Figures were generated in cBioPortal.org.247,248,249
