Table 1 Maternal characteristics at enrollment in the total study population and in SIMPLE score subgroups.

From: Maternal first trimester SIMPLE nutritional score, early markers of placental function and pregnancy outcome: a prospective multicenter Italian study (SIMPLE study)

Maternal characteristic

Total population (n = 2363)

SIMPLE score < 6 (n = 325)

SIMPLE score ≥ 6 (n = 1934)

p

Age, years, median (range)

33.0 (18.0–46.0)

32.0 (18.0; 45.0)

33.0 (18.0; 46.0)

<0.01

BMI, kg/m2, median (range)

22.6 (14.7; 49.1)

22.0 (15.9; 40.2)

21.7 (14.7; 46.3)

0.22

Obesity, n (%)

130 (5.6)

23 (7.2)

101 (5.3)

0.16

GWG, kg, median (range)

1.2 (−12.0; 17.0)

1.0 (−12.0; 9.0)

1.0 (−11.0; 17.0)

0.80

Ethnicity, non-caucasian, n (%)

148 (6.3)

31 (9.5)

111 (5.7)

<0.01

Conception mode, n (%)

    

 Spontaneous

2256 (96.7)

315 (97.2)

1869 (96.9)

 

 ART

77 (3.3)

9 (2.8)

59 (3.1)

0.78

Education, n (%)

    

 Low

239 (10.3)

63 (19.5)

171 (8.9)

 

 Intermediate

892 (38.3)

141 (43.7)

716 (37.2)

 

 High

1198 (51.4)

119 (36.8)

1039 (54.0)

<0.01

Nulliparous, n (%)

1353 (58.0)

183 (56.5)

1112 (57.7)

0.69

Smoking habit, n (%)

    

 Ex/never

2175 (92.2)

287 (88.6)

1817 (94.2)

 

 Current

158 (6.8)

37 (11.4)

111 (5.8)

<0.01

Alcohol consumption

    

 Yes

74 (3.5)

5 (1.7)

67 (3.8)

0.06

SIMPLE score, median (range)

7 (1–10)

5 (1–5)

8 (6–10)

 

SIMPLE score <6, n (%)

325 (14.4)

   
  1. Chi square and Kruskal–Wallis or t-tests as appropriate based on normality test were used to compare baseline characteristics between the two subgroups.
  2. BMI body mass index, GWG gestational weight gain, ART assisted reproductive technology.