Table 4 Results from multi-adjusted logistic regression models on the associations between SIMPLE score subgroup (SIMPLE score ≥6 versus <6, independent variable) and pregnancy adverse outcomes (dependent variables).

From: Maternal first trimester SIMPLE nutritional score, early markers of placental function and pregnancy outcome: a prospective multicenter Italian study (SIMPLE study)

 

Univariate

Multivariate

Delivery outcome

β

95% CI

OR (95% CI)

β

95% CI

OR (95% CI)

Gestational hypertension

−0.282

−0.943; 0.380

0.75 (0.39–1.46)

0.073

−0.746; 0.892

1.08 (0.47–2.44)

Preeclampsia

1.157

−0.854; 3.168

3.18 (0.43–23.76)

1.129

−0.915; 3.173

3.09 (0.40–23.88)

FGR

0.261

−0.676; 1.197

1.30 (0.51–3.31)

0.633

−0.562; 1.829

1.88 (0.57–6.23)

GDM

−0.022

−0.452; 0.409

0.98 (0.64–1.51)

0.031

−0.441; 0.504

1.03 (0.64–1.66)

Prematurity

−0.369

−0.897; 0.160

0.69 (0.41–1.17)

−0.390

−0.957; 0.177

0.68 (0.38–1.19)

Delivery mode, CS

−0.507

−0.796; −0.217

0.60 (0.45–0.80)

−0.434

−0.759; −0.110

0.65 (0.47–0.90)

  1. All models are adjusted for maternal age (continuous), BMI (continuous), smoke (current versus ex/never), alcohol consumption (yes/no), conception mode (spontaneous versus ART), parity (nulliparous versus multiparous), fetal sex (male versus female), unit of enrolment.
  2. Bold-type highlights the significant results (p values <0.05).
  3. FGR fetal growth restriction, GDM gestational diabetes mellitus, CS cesarean section.
Back to article page