Table 1 Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and kappa agreement of EyeArt for detection of any varying degrees of DR with ophthalmologist grading as reference standard
Retinopathy | Sensitivity, % (95% CI) | Specificity, % (95% CI) | PPV (95% CI) | NPV (95% CI) | Kappa (95% CI) | p-value |
|---|---|---|---|---|---|---|
Any DR | 95.8 (92.9, 98.7) | 80.2 (72.6, 87.8) | 89.7 (85.5, 93.8) | 91.4 (85.7, 97.1) | 0.78 (0.71, 0.86) | <0.001 |
DME | 97 (91.5, 99.4) | 75.8 (69.7, 81.8) | 67.4 (59.7, 75.0) | 98.0 (94.3, 99.6) | 0.66 (0.58, 0.74) | <0.001 |
PDR | 78.1 (63.8, 83.3) | 89.8 (86.1, 93.4) | 48.1 (34.5, 61.7) | 97.1 (95.0, 99.2) | 0.53 (0.4, 0.67) | <0.001 |
STDR | 99.1 (95.1, 99.9) | 80.4 (73.9, 85.9) | 75.3 (68.4, 82.3) | 99.3 (96.3, 100) | 0.75 (0.67, 0.83) | <0.001 |
RDR | 99.3 (96.1, 99.9) | 68.8 (61.5, 76.2) | 74.6 (68.4, 80.8) | 99.1 (97.2, 100) | 0.67 (0.59, 0.75) | <0.001 |