Fig. 1

a World map of reported cases with various TGFBI mutations. Each bubble placed over a region or country contains the reported case information, such as ethnicities, mutations, and case numbers. The map illustrates that TGFBI mutations cases are reported all over the world, except for in regions with limited research capacity or language difficulties for publication. Very few cases were reported from South America, and no case. reports were identified from Africa or Russia. b The red bubble points at London, England as an example of the information contained within the bubble. The legend on the left shows the reported mutations, ethnicity and total case numbers for each reported mutation