Table 2 Structural and perfusion parameters in the peripapillary and macular region of the participants between different myopia groups

From: Association between retinal microvasculature and optic disc alterations in high myopia

Variable

EM (N = 85)

MIM (N = 211)

MOM (N = 243)

HM (N = 221)

P value

Post hoc

pReT, µm

290.71 ± 16.16

285.87 ± 13.42

281.53 ± 14.07

278.21 ± 15.43

<0.0001

EM > MOM/HM; MIM > MOM/HM

pRNFLT, µm

102.19 ± 10.05

102.18 ± 7.14

102.26 ± 8.03

102.93 ± 9.13

0.8366

/

pGCLT + pRNFL, µm

146.21 ± 11.48

144.30 ± 8.46

142.74 ± 9.04

142.30 ± 10.34

0.0137

EM > MOM; EM > HM

pChT, µm

154.39 ± 42.71

145.43 ± 41.40

137.79 ± 41.90

123.25 ± 40.01

<0.0001

EM > MOM > HM; MIM > HM

Area of PPA,mm2

0.09 ± 0.08

0.14 ± 0.10

0.19 ± 0.14

0.26 ± 0.17

<0.0001

EM < MIM < MOM < HM

Tilted disc ratio

0.83 ± 0.08

0.80 ± 0.09

0.78 ± 0.09

0.76 ± 0.08

<0.0001

EM > MIM > HM; EM > MOM

RPC vessel density,%

45.02 ± 3.76

44.40 ± 3.62

43.13 ± 3.99

42.98 ± 4.42

<0.0001

EM > MOM/HM; MIM > MOM/HM

mReT, µm

281.59 ± 12.44

277.61 ± 11.99

275.95 ± 10.95

274.26 ± 12.74

<0.0001

EM > MOM; MIM > HM;EM > HM

mRNFLT, µm

40.57 ± 4.28

40.56 ± 4.69

40.61 ± 5.46

39.98 ± 5.39

0.5402

/

mGCLT + RNFL, µm

111.39 ± 6.57

110.07 ± 5.82

109.57 ± 5.85

109.21 ± 6.08

0.0684

/

mChT, µm

249.54 ± 52.95

233.15 ± 54.11

212.46 ± 58.40

191.73 ± 56.24

<0.0001

EM/MIM > MOM > HM

Foveal ReT, µm

230.38 ± 17.63

226.88 ± 18.36

227.16 ± 16.98

227.53 ± 19.14

0.4807

/

Foveal RNFLT, µm

7.48 ± 2.98

8.04 ± 3.86

8.19 ± 3.47

7.36 ± 3.48

0.0462

/

Foveal GCLT + RNFLT, µm

52.17 ± 7.93

51.85 ± 9.71

51.69 ± 7.80

50.41 ± 8.91

0.3151

/

Foveal ChT, µm

264.19 ± 60.69

245.24 ± 64.14

216.26 ± 68.42

190.67 ± 64.88

<0.0001

EM/MIM > MOM > HM

Area of FAZ, mm2

0.35 ± 0.10

0.36 ± 0.11

0.37 ± 0.11

0.39 ± 0.13

0.0052

EM/MIM < HMfoveal

Superficial parafoveal vessel density, %

48.80 ± 3.62

48.50 ± 3.94

48.05 ± 3.98

47.59 ± 3.88

0.0329

/

Deep parafoveal Vessel density, %

60.52 ± 3.16

59.98 ± 3.78

58.93 ± 3.96

57.49 ± 4.96

<0.0001

EM/MIM > MOM > HM

  1. Numbers displayed are mean ± standard deviation. All values were calculated using the one-way analysis of variance. Tukey multiple comparisons were performed among the four axial length groups
  2. ChT choroidal thickness, EM emmetropia, FAZ foveal avascular zone, GCLT ganglion cell layer thickness, HM high myopia, mChT macular choroidal thickness, mGCLT macular ganglion cell layer thickness, MIM mild myopia, MOM moderate myopia, mRNFLT macular retinal nerve fiber layer thickness, mRT macular retinal thickness, pChT peripapillary choroidal thickness, pGCLT peripapillary ganglion cell layer thickness, PPA parapapillary atrophy, pRNFLT peripapillary retinal nerve fiber layer thickness, pReT peripapillary retinal thickness, ReT retinal thickness, RPC radial peripapillary capillary, RNFLT retinal nerve fiber layer thickness
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