Table 1 Baseline characteristics of the patients with Dysthyroid Optic Neuropathy (DON).
From: Evaluation of medical and surgical decompression in patients with dysthyroid optic neuropathy
Surgical decompression (n = 30 eyes) (n = 18 patients) | Medical decompression only (n = 16 eyes) (n = 7 patients) | P-Value | |
|---|---|---|---|
Female/Male | 16/2 | 4/3 | – |
Age (mean) | 55 (range 38–85) | 62 (range 45–75) | 0.862 |
Observation period [days] (mean) | 303 (range 95–636) | 361 (range 95–1601) | 0.481 |
Prior treatment | |||
Radioiodine Treatment | 5 | 3 | – |
Thyroidectomy prior to DON diagnosis | 10 | 3 | |
Thyroidectomy after the diagnosis of DON | 3 | 1 | |
None | 1 | 1 | |
Systemic treatment of GO | |||
L-Thyroxin | 11 | 2 | – |
Selenium (300 μgr/ daily) | 4 | 0 | |
Carbimazole | 2 | 0 | |
None | 4 | 5 | |
Smoking status | |||
Current smoker | 10 | 5 | – |
Ex-Smoker | 3 | 0 | |
Never smoked | 5 | 2 | |
Δ End of STX – Surgery [days] | 75 (range −36–331) | – | |
CAS Grading (Visit 1) (median) | 7/10 (range 3–8) | 5/10 (range 4–8) | 0.247 |
Intraocular Pressure (Visit 1) (mmHg) | 17.00 (range 12–25) | 17.50 (range 12–21) | 0.268 |
fT3 (pmol/liter) | 2.88 (range 0.90–3.90) | 2.74 (range 2.26–3.30) | 0.296 |
fT4 (pmol/liter) | 1.56 (range 0.55–12.10) | 1.19 (range 1.00–5.60) | 0.370 |
TSH (mU/liter) | 0.33 (range 0.01–7.90) | 2.01 (range 0.01–15.20) | 0.203 |
TSH-R (IU/liter) | 17.40 (range 1.00–40.00) | 6.60 (range 0.71–38.00) | 0.333 |
