Abstract
Purpose
To investigate the risk factors associated with retinal detachment recurrence after first vitrectomy in high myopic eyes with macular hole retinal detachment (MHRD).
Methods
Patients with high myopic eyes with MHRD who underwent pars plana vitrectomy and silicone oil (SO) tamponade with a follow-up period more than 12 months and more than 3 months after SO removal were included in this retrospective study. Logistic regression was performed to determine the risk factors associated with retinal re-detachment.
Results
A total of 45 eyes from 43 patients were included in this study (11 male and 34 female patients). The retinal re-detachment rate after the first removal of silicon oil was 35.5% (16/45) in a mean postoperative follow-up time of 35.64 ± 32.94 months. Complete macular atrophy on fundus photography (odds ratio (OR) = 17.021, 95% confidence interval (95% CI): 2.218–130.609, p = 0.006) was a risk factor for MHRD after SO removal, while internal limiting membrane (ILM) peeling (OR = 0.091, 95% CI: 0.013–0.633, p = 0.015) and duration of SO tamponade (OR = 0.667, 95% CI: 0.454–0.980, p = 0.039) were protective factors.
Conclusion
For high myopic eyes with MHRD, complete macular atrophy was a significant risk factor for retinal re-detachment after silicon oil removal. ILM peeling and the duration of silicon oil tamponade were protective factors.
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Data availability
The datasets used during the current study are available from the corresponding author on reasonable request. Informed consent for publication of the clinical dataset from participants has been obtained.
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Acknowledgements
We thank Dong Chongya for his help in statistical analysis and American Journal Experts (AJE) for providing medical English editing for this manuscript.
Funding
The study was supported by Capital clinical diagnosis and treatment technology research and demonstration application project of China (Grant Z191100006619029) and the Research Fund for Science and Technology Program of Beijing (No. Z161100000516037). The funders had no role in the study design, data collection and analysis, decision to publish or preparation of the paper.
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This retrospective study was approved by the Peking University People’s Hospital Review Board and adhered to the tenets of the Declaration of Helsinki and Health Insurance Portability and Accountability Act.
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Written informed consent was obtained from all individual participants included in the study.
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Li, M., Tang, J., Jia, Z. et al. Long-term follow-up of primary silicone oil tamponade for retinal detachment secondary to macular hole in highly myopic eyes: a prognostic factor analysis. Eye 35, 625–631 (2021). https://doi.org/10.1038/s41433-020-0922-0
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DOI: https://doi.org/10.1038/s41433-020-0922-0
