Abstract
Purpose
To describe clinical characteristics and visual outcomes of non-traumatic open globe injuries.
Setting
A level 1 trauma centre in a large urban medical centre.
Design
Retrospective study.
Methods
Charts of non-traumatic open globe patients admitted to MHH-TMC from 1/2010 to 3/2015 were reviewed for demographics, cause, clinical characteristics, visual acuity (VA) and enucleation.
Results
Thirty eyes were included: 15 (50%) were males with a mean age of 47 (±28) years. All presented with zone 1 injury. Twenty-five (83%) had a perforated corneal ulcer. Presenting VA was count fingers (n = 3, 10%) to NLP (n = 6, 20%). Twenty-four (80%) involved infection, 5 (17%) congenital, 3 (10%) chemical burn and 2 (7%) neurotrophic. Conjunctival injection (n = 22, 77%), corneal opacification (n = 20, 71%) and relative afferent pupillary defect (n = 9, 44%) were common. After treatment, 23 (88%) were worse than 6/60 (20/200), 9 (35%) were NLP and 8 (27%) required enucleation.
Conclusions
Often non-traumatic open globe injuries are zone 1 and due to perforated infectious ulcers. Compared to previously reported traumatic injuries, these have higher rates of enucleation (27% vs 8%) and poorer final VA (88% vs 68% worse than 6/60 20/200).
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Funding
This work was supported in part by National Eye Institution Vision Core Grant P30EY028102 and Research to Prevent Blindness. Funding sources were not involved in collection, analysis or collection of data, or writing of this manuscript.
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AWG collected data and wrote first drafts of the manuscript. ELC contributed to the conception and review of the article. JZF, MLP, AZC, KR, and ELC edited subsequent drafts and revisions. AZC additionally contributed to data analysis. All authors contributed to manuscript revision, read, and approved the submitted version.
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Gross, A.W., Fan, J.Z., Pfeiffer, M.L. et al. Non-traumatic open globe injuries: presenting characteristics and visual outcomes. Eye 36, 2323–2327 (2022). https://doi.org/10.1038/s41433-021-01869-4
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DOI: https://doi.org/10.1038/s41433-021-01869-4
