Table 1 Associations (univariable analysis) between central corneal thickness systemic parameters in the Ural Eye and Medical Study.
Parameter | Interval | Standardized regression coefficient beta | Non- standardized regression coefficient B | 95% confidence interval of B | P-Value |
---|---|---|---|---|---|
Age | 1-year intervals | −0.09 | −0.27 | −0.35, −0.19 | <0.001 |
Gender | Men / Women | −0.06 | −3.72 | −5.47, −1.97 | <0.001 |
Region of habitation | Rural / Urban | 0.14 | 9.47 | 7.72, 11.2 | <0.001 |
Ethnicity | Any other ethnicity / Russian | 0.12 | 10.1 | 7.91, 12.2 | <0.001 |
Body height | 1 cm | 0.07 | 0.27 | 0.17, 0.37 | <0.001 |
Body weight | kg | 0.08 | 0.19 | 0.13, 0.25 | <0.001 |
Body mass index | kg/m2 | 0.05 | 0.31 | 0.14, 0.49 | <0.001 |
Waist circumference | cm | 0.03 | 0.06 | −0.001, 0.13 | 0.053 |
Hip circumference | cm | 0.01 | 0.03 | −0.04, 0.10 | 0.44 |
Waist/hip circumference ratio | Ratio | 0.03 | 9.21 | −0.39, 18.8 | 0.06 |
Socioeconomic Score | Score | 0.09 | 2.00 | 1.43, 2.57 | <0.001 |
Level of education | Illiteracy / Passing 5th Grade / 8th Grade / 10th Grade / 11th Grade / Graduates / Specialized Secondary Education / Post Graduates | 0.10 | 2.36 | 1.76, 2.96 | <0.001 |
Physical activity Score | Score | 0.01 | 0.03 | −0.09, 0.14 | 0.64 |
Smoking, currently | No / Yes | 0.04 | 4.72 | 1.65, 6.89 | 0.001 |
Smoking, package years | Number | 0.03 | 0.08 | 0.01, 0.15 | 0.03 |
Alcohol consumption, any | No / Yes | 0.03 | 2.17 | 0.05, 4.29 | 0.045 |
In a week how many days do you eat fruits? | Number of days | 0.01 | 0.09 | −0.35, 0.53 | 0.67 |
In a week how many days do you eat vegetables? | Number of days | −0.01 | −0.25 | −0.86, 0.37 | 0.43 |
How much salt do you consume every day? | g | 0.01 | 0.15 | −0.24, 0.54 | 0.44 |
History of cardiovascular disorders including stroke | No / Yes | 0.02 | 1.37 | −0.68, 3.42 | 0.19 |
History of angina pectoris | No / Yes | 0.01 | 1.11 | −1.90, 4.13 | 0.47 |
History of asthma | No / Yes | 0.01 | 2.73 | −2.56, 8.03 | 0.31 |
History of arthritis | No / Yes | −0.02 | −1.38 | −3.32, 0.57 | 0.17 |
History of previous bone fractures | No / Yes | 0.02 | 1.60 | −0.38, 3.58 | 0.11 |
History of low back pain | No / Yes | 0.02 | 1.34 | −0.49, 3.17 | 0.15 |
History of thoracic spine pain | No / Yes | −0.004 | 0.32 | −2.47, 1.82 | 0.77 |
History of neck pain | No / Yes | 0.02 | 1.59 | −0.41, 3.60 | 0.12 |
History of headache | No / Yes | −0.01 | −0.91 | −2.74, 0.91 | 0.33 |
History of cancer | No / Yes | 0.01 | 2.47 | −2.68, 7.62 | 0.35 |
History of dementia | No / Yes | −0.02 | 7.73 | −19.0, 3.55 | 0.18 |
History of diarrhoea | No / Yes | −0.001 | −0.35 | −13.2, 12.5 | 0.96 |
History of iron-deficiency anaemia | No / Yes | 0.01 | 1.29 | −2.65, 5.23 | 0.52 |
History of low blood pressure and hospital admittance | No / Yes | 0.01 | 1.97 | −2.72, 6.67 | 0.41 |
History of osteoarthritis | No / Yes | 0.00 | 0.04 | −2.31, 2.40 | 0.97 |
History of skin disease | No / Yes | 0.02 | 2.69 | −1.37, 6.74 | 0.19 |
History of thyreopathy | No / Yes | 0.004 | 0.41 | −2.45, 3.26 | 0.78 |
History of tumbling | No / Yes | 0.02 | 1.72 | −0.51, 3.95 | 0.13 |
History of unconsciousness | No / Yes | 0.03 | 3.20 | 0.04, 6.36 | 0.047 |
Age of the last menstrual bleeding | Years | 0.02 | 0.15 | −0.12, 0.42 | 0.28 |
Age of last regular menstrual bleeding | Years | 0.03 | 0.17 | −0.10, 0.45 | 0.22 |
History of menopause | No / Yes | −0.05 | −4.52 | −7.60, 1.45 | 0.004 |
History of diabetes mellitus | No / Yes | 0.04 | 4.36 | 1.24, 7.49 | 0.006 |
Serum concentration of: | |||||
Alanine aminotransferase | IU/L | 0.04 | 0.10 | 0.03, 0.18 | 0.005 |
Aspartate aminotransferase | IU/L | 0.03 | 0.10 | 0.02, 0.18 | 0.01 |
Aspartate aminotransferase-to- Alanine aminotransferase ratio | Ratio | −0.003 | −0.19 | −1.97, 1.58 | 0.83 |
Bilirubin, total | µmol/L | 0.04 | 0.11 | 0.04, 0.19 | 0.004 |
High-density lipoproteins | mmol/L | −0.01 | −0.52 | −1.54, 0.51 | 0.32 |
Low-density lipoproteins | mmol/L | −0.003 | −0.10 | −0.87, 0.67 | 0.80 |
Cholesterol | mmol/L | 0.01 | 0.24 | −0.28, 0.75 | 0.36 |
Triglycerides | mmol/L | 0.03 | 1.17 | −0.06, 2.39 | 0.06 |
Rheumatoid factor | IU/mL | −0.02 | −0.60 | −1.54, 0.34 | 0.21 |
Erythrocyte sedimentation rate | Mm/min | −0.6 | −0.19 | −0.27, −0.11 | <0.001 |
Glucose | mmol/L | 0,02 | 0.33 | −0.19, 0.85 | 0.22 |
Urea | mmol/L | −0.04 | −0.90 | −1.49, −0.30 | 0.003 |
Creatinine | µmol/L | 0.003 | 0.005 | −0.03, 0.04 | 0.79 |
Haemoglobin | g/L | 0.07 | 0.15 | 0.09, 0.21 | <0.001 |
Erythrocyte count | 106 cells / µL | 0.06 | 5.52 | 3.24, 7.79 | <0.001 |
Leucocyte count | 109 cells / L | 0.01 | 0.14 | −0.47, 0.75 | 0.65 |
Rod-core granulocytes | % of leucocytes | −0.01 | −0.17 | −0.80, 0.47 | 0.61 |
Segment nuclear granulocyte | % of leucocytes | 0.03 | 0.15 | 0.03, 0.27 | 0.01 |
Eosinophil granulocytes | % of leucocytes | −0.01 | −0.39 | −1.25, 0.47 | 0.37 |
Lymphocytes | % of leucocytes | −0.01 | −0.06 | −0.20, 0.08 | 0.40 |
Monocytes | % of leucocytes | −0.04 | −0.51 | −0.89, −0.13 | 0.009 |
Diabetes mellitus, prevalence | Yes/No | 0.04 | 4.32 | 1.59, 7.04 | 0.002 |
Estimated glomerular filtration rate | 30 mL/min/1.73 m² | 0.05 | 0.09 | 0.04, 0.13 | <0.001 |
Stage of chronic kidney disease | 0–5 | −0.04 | −0.16 | −0.28, −0.04 | 0.007 |
Anaemia | No / Yes | −0.04 | −3.24 | −5.29, −1.19 | 0.002 |
Blood pressure, systolic | mm Hg | 0.01 | 0.01 | −0.03, 0.05 | 0.69 |
Blood pressure, diastolic | mm Hg | 0.02 | 0.08 | −0.04, 0.19 | 0.18 |
Blood pressure, mean | mm Hg | 0.02 | 0.05 | −0.02, 0.12 | 0.15 |
Arterial hypertension | Yes/No | 0.01 | 0.76 | −0.98, 2.50 | 0.39 |
Arterial hypertension, stage | 0–4 | 0.01 | 0.22 | −0.62, 1–07 | 0.61 |
Ankle-brachial pressure index, right | 0.002 | 0.43 | −5.91, 6.77 | 0.89 | |
Prevalence of chronic obstructive pulmonary disease | Yes/No | 0.01 | 1.19 | −2.42, 4.79 | 0.52 |
Hearing loss | Hearing loss score (0–44) | −0.05 | −0.15 | −0.23, −0.06 | 0.001 |
Depression Score | Depression score unit (range: −4 to +15) | −0.02 | −0.13 | −0.36, 0.10 | 0.27 |
State-Trait Anxiety Inventory | State-Trait Anxiety Inventory Score (range: −7 to 13) | −0.03 | −0.23 | −0.48, 0.01 | 0.06 |
Manual dynamometry, right hand | dekaNewton | 0.09 | 0.26 | 0.18, 0.34 | <0.001 |
Manual dynamometry, right hand | dekaNewton | 0.09 | 0.27 | −0.19, 0.35 | <0.001 |