Fig. 5: Post-acquisition spectral domain optical coherence tomography image processing showing binarization to calculate the choroidal vascularity index.
From: Choroidal vascularity index and choroidal thickness: potential biomarkers in retinitis pigmentosa

Binarization is made on the region of interest (ROI) using Niblack’s auto local threshold technique, to analyze mean and standard deviation of dark and light pixels in the ROI.