Abstract
A 55-year-old man while being evaluated for unexplained weight loss was found to have multiple metabolically active lymph nodes on positron emission tomography-computed tomography (PET-CT) scan, and biopsy from right axillary lymph node demonstrated multiple histiocytes with emperipolesis with S100 positivity, consistent with Rosai-Dorfman disease.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 18 print issues and online access
$259.00 per year
only $14.39 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout

Author information
Authors and Affiliations
Contributions
Concept and design: Dr Swati Phuljhele and Dr Himani Thakur. Acquisition of the histopathology image: Dr Saumyaranjan Mallick. Drafting of the manuscript: Dr Himani Thakur. Critical revision of the manuscript for important intellectual content: Dr Rohit Saxena and Dr Rebika Dhiman. The manuscript is an honest work and has been approved by all the authors.
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Phuljhele, S., Thakur, H., Saxena, R. et al. Optic neuritis in Rosai Dorfman disease. Eye 39 (Suppl 1), 102–103 (2025). https://doi.org/10.1038/s41433-024-03369-7
Received:
Revised:
Accepted:
Published:
Issue date:
DOI: https://doi.org/10.1038/s41433-024-03369-7