Table 2 Clinical features at baseline.

From: Visual and anatomical failure of anti-VEGF therapy for retinal vascular diseases: a survival analysis of real-world data

Baseline eye-level clinical features

 

DMO (N = 2107)

CRVO (N = 413)

BRVO (N = 757)

Overall (N = 3227)

Baseline VA (ETDRS letters)

 Mean (SD)

61 (16)

47 (21)

56 (17)

58 (17)

 Median (IQR)

65 (18)

50 (27)

59 (24)

61 (20)

Baseline VA greater than or equal to 70 ETDRS letters

 <70

1367 (64.9%)

357 (86.4%)

569 (75.2%)

2293 (70.0%)

 70 or over

740 (35.1%)

56 (13.6%)

188 (24.8%)

984 (30.0%)

Baseline central subfoveal thickness (microns)

 Mean (SD)

420 (120)

510 (170)

440 (140)

430 (140)

 Median (IQR)

400 (140)

510 (240)

430 (200)

410 (170)

Intraretinal fluid (nL)

 Mean (SD)

76 (85)

150 (150)

130 (120)

97 (110)

 Median (IQR)

47 (86)

110 (180)

91 (140)

62 (110)

Subretinal fluid (nL)

 Mean (SD)

80 (350)

380 (730)

340 (660)

180 (510)

 Median (IQR)

0.12 (15)

47 (430)

25 (390)

1.4 (67)

Phakic status

 Aphakic

3 (0.1%)

0 (0.0%)

1 (0.1%)

4 (0.1%)

 Phakic

1170 (55.5%)

315 (76.3%)

562 (74.2%)

2047 (62.5%)

 Pseudophakic

564 (26.8%)

86 (20.8%)

174 (23.0%)

824 (25.2%)

 Missing

370 (17.6%)

12 (2.9%)

20 (2.6%)

402 (12.3%)

Anti-VEGF agent

 Aflibercept

1355 (64.3%)

385 (93.2%)

514 (67.9%)

2254 (68.8%)

 Ranibizumab

752 (35.7%)

28 (6.8%)

243 (32.1%)

1023 (31.2%)

  1. Baseline time point was taken to be time at initiation of intravitreal anti-VEGF therapy.
  2. DMO diabetic macular oedema, CRVO central retinal vein occlusion, BRVO branch retinal vein occlusion, VA visual acuity, ETDRS early treatment diabetic retinopathy study.