Table 2 Fluid reduction and retreatment interval for all eyes stratified by retinal fluid compartments.

From: Retinal fluid quantification using a novel deep learning algorithm in patients treated with faricimab in the TRUCKEE study

After Treatment #

Eyes (n/N)

All Eyes with IRF & SRF

Eyes (n/N)

Eyes with > 10-nL Fluid

% with fluid reduction

Mean Retreatment Interval (days)

% with fluid reduction

Mean Retreatment Intervals (days)

1

100/123

81.3%

54.3

89/109

81.7%

52.6

2

83/100

83.0%

57.6

76/91

83.5%

50.4

3

68/81

84.0%

57.5

63/74

85.1%

58.6

4

52/61

85.3%

53.7

47/56

83.9%

53.2

5

33/39

84.6%

62.6

30/36

83.3%

64.7

After Treatment #

Eyes (n/N)

All Eyes with IRF only

Eyes (n/N)

Eyes with > 10-nL Fluid

% with fluid reduction

Mean Retreatment Interval (days)

% with fluid reduction

Mean Retreatment Intervals (days)

1

66/104

63.5%

51.9

29/50

58.0%

47.0

2

64/82

77.1%

48.5

34/46

73.9%

44.6

3

50/70

71.4%

53.4

29/39

65.9%

48.0

4

35/55

63.5%

56.4

22/37

59.5%

54.8

5

32/45

71.1%

53.1

19/32

59.4%

51.7

After Treatment #

Eyes (n/N)

All Eyes with SRF only

Eyes (n/N)

Eyes with > 10-nL Fluid

% with fluid reduction

Mean Retreatment Interval (days)

% with fluid reduction

Mean Retreatment Intervals (days)

1

94/123

76.4%

50.7

62/87

71.3%

47.9

2

82/103

79.6%

53.9

59/73

80.8%

54.3

3

61/81

75.3%

56.2

43/60

71.7%

48.0

4

57/68

83.8%

55.1

43/53

81.1%

55.6

5

41/51

80.4%

60.7

31/41

75.6%

59.7

  1. We see a stable proportion of over 80% of eyes with both IRF and SRF demonstrating improvements in total retinal fluid. Eyes with IRF only demonstrate a proportion greater than 60% of patients with improvement. Eyes with SRF only demonstrate a proportion greater than 75% of patients with improvement.
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