Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Predicting post-surgery change in visual acuity after successful repair of macula-off retinal detachments: findings from a large prospective UK cohort study

Abstract

Objective

To identify risk factors affecting the change in visual acuity in successfully re-attached macula-off rhegmatogenous retinal detachment (RD) surgery.

Design

A cohort study, using an online database, of visual outcomes for 2770 macula-off retinal detachments that were successfully re-attached by vitrectomy and internal tamponade. The database included detailed retinal diagrams of each detachment.

Main outcome measure

The change in LogMAR visual acuity from pre-operatively to post-operatively.

Results

Male patients accounted for 64.6% of the sample and the median age was 63 years old. The median pre-operative VA was counting fingers (LogMAR 1.98); this improved to 0.30 LogMAR post-operatively. An improvement in VA of ≥0.30 LogMAR was achieved by 88.0% eyes. The change in VA model identified the preoperative VA, patient age, duration of central vision loss, lens status at follow up, extent of detachment, and the number of breaks in the detached retina, as factors influencing the change in VA. The model had an adjusted R2 of 0.749, and for 75.5% of eyes, the model prediction was within ±0.30 LogMAR of the recorded VA change.

Conclusions

Greater post-operative visual acuity improvement was more likely in eyes that were pseudophakic at follow up, and had shorter durations of central vision loss. Non modifiable factors associated with greater vision improvement included worse presenting vision, younger age, less extensive detachment and less than three breaks in the detached retina. These results confirm that prompt surgery improves functional outcomes in successfully treated macula off retinal detachments irrespective of presenting visual acuity.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Yorston D, Donachie PHJ, Laidlaw DA, Steel DH, Sparrow JM, Aylward GW, et al. Factors affecting visual recovery after successful repair of macula-off retinal detachments: findings from a large prospective UK cohort study. Eye. 2021;35:1431–9.

    Article  CAS  PubMed  Google Scholar 

  2. Sothivannan A, Eshtiaghi A, Dhoot AS, Popovic MM, Garg SJ, Kertes PJ, et al. Impact of the Time to Surgery on Visual Outcomes for Rhegmatogenous Retinal Detachment Repair: A Meta-Analysis. Am J Ophthalmol. 2022;244:19–29.

    Article  PubMed  Google Scholar 

  3. Williamson TH, Shunmugam M, Rodrigues I, Dogramaci M, Lee E. Characteristics of rhegmatogenous retinal detachment and their relationship to visual outcome. Eye. 2013;27:1063–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. van Bussel EM, van der Valk R, Bijlsma WR, Heij ECL. Impact of duration of macula-off retinal detachment on visual outcome. Retina. 2014;34:1917–25.

    Article  PubMed  Google Scholar 

  5. Greven MA, Leng T, Silva RA, Leung LSB, Karth PA, Moshfeghi DM, et al. Reductions in final visual acuity occur even within the first 3 days after a macula-off retinal detachment. Br J Ophthalmol. 2019;103:1503–6.

    Article  PubMed  Google Scholar 

  6. Lee CS, Shaver K, Yun SH, Kim D, Wen S, Ghorayeb G. Comparison of the visual outcome between macula-on and macula-off rhegmatogenous retinal detachment based on the duration of macular detachment. BMJ Open Ophthalmol. 2021;6:615.

    Google Scholar 

  7. Frings A, Markau N, Katz T, Stemplewitz B, Skevas C, Druchkiv V, et al. Visual recovery after retinal detachment with macula-off: is surgery within the first 72 h better than after? Br J Ophthalmol. 2016;100:1466–9.

    Article  PubMed  Google Scholar 

  8. Put MAJ van de, Croonen D, Nolte IM, Japing WJ, Hooymans JMM, et al. Postoperative Recovery of Visual Function after Macula-Off Rhegmatogenous Retinal Detachment. Vavvas D, editor. PLoS ONE. 2014;9:e99787.

  9. Miyake M, Nakao Sya, Morino K, Yasukura S, Mori Y, Ishihara K, et al. Effect of Duration of Macular Detachment on Visual Prognosis after Surgery for Macula-Off Retinal Detachment. Ophthalmol Retina. 2023;7:375–82.

    Article  PubMed  Google Scholar 

  10. Baumann C, Kaye SB, Steel DH. Reversing the paradigm on the urgency of acute retinal detachments defined by their foveal status: when off may be more urgent than on. BMJ Open Ophthalmol. 2024;9:e001668.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Barequet D, Shemesh R, Zvi D, Cohen R, Trivizki O, Schwartz S, et al. Functional and anatomical outcomes of fovea on, fovea off and fovea-splitting rhegmatogenous retinal detachment. Graefes Arch Clin Exp Ophthalmol. 2023;261:3187–92.

    Article  PubMed  Google Scholar 

  12. Cavallini GM, Masini C, Volante V, Pupino A, Campi L, Pelloni S. Visual Recovery after Scleral Buckling for Macula-Off Retinal Detachments: An Optical Coherence Tomography Study. Eur J Ophthalmol. 2007;17:790–6.

    Article  CAS  PubMed  Google Scholar 

  13. Liu F, Meyer CH, Mennel S, Hoerle S, Kroll P. Visual recovery after scleral buckling surgery in macula-off rhegmatogenous retinal detachment. Ophthalmol J Int Ophtalmol Int J Ophthalmol Z Augenheilkd. 2006;220:174–80.

    Google Scholar 

  14. Ross W, Lavina A, Russell M, Maberley D. The Correlation between Height of Macular Detachment and Visual Outcome in Macula-Off Retinal Detachments of ≤7 Days’ Duration. Ophthalmology. 2005;112:1213–7.

    Article  PubMed  Google Scholar 

  15. Royal College of Ophthalmologists. RCOphth Retinal Detachment Dataset. 2024. Available from: www.rcophth.ac.uk/wp-content/uploads/2020/08/2011_PROF_158_Retinal-Detachment-Dataset.pdf.

  16. Lange C, Feltgen N, Junker B, Schulze-Bonsel K, Bach M. Resolving the clinical acuity categories ‘hand motion’ and ‘counting fingers’ using the Freiburg Visual Acuity Test (FrACT). Graefes Arch Clin Exp Ophthalmol Albrecht Von Graefes Arch Klin Exp Ophthalmol. 2009;247:137–42.

    Article  CAS  Google Scholar 

  17. Murtaza F, Goud R, Belhouari S, Eng KT, Mandelcorn ED, da Costa BR, et al. Prognostic Features of Preoperative OCT in Retinal Detachments: A Systematic Review and Meta-analysis. Ophthalmol Retina. 2023;7:383–97.

    Article  PubMed  Google Scholar 

  18. Klaas JE, Siedlecki J, Steel DH, Laidlaw DAH, Priglinger S. How should we report the foveal status in eyes with “macula-off” retinal detachment? Eye. 2023;37:228–34.

    Article  PubMed  Google Scholar 

  19. Lecleire-Collet A, Muraine M, Menard JF, Brasseur G. Predictive visual outcome after macula-off retinal detachment surgery using optical coherence tomography. Retina Phila Pa. 2005;25:44–53.

    Article  Google Scholar 

  20. Baumann C, Almarzooqi A, Johannigmann-Malek N, Maier M, Kaye S. Importance of subfoveal fluid height on visual outcome in macula-off retinal detachments. Br J Ophthalmol. 2023;107:1467–71.

    Article  Google Scholar 

  21. Ng H, Heij ECL, van Meurs JC. The duration of macular detachment in retinal detachment is difficult to determine. Acta Ophthalmol. 2019. https://doi.org/10.1111/aos.14294.

  22. The SPR Study Group, Heussen N, Feltgen N, Walter P, Hoerauf H, Hilgers RD, et al. Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR Study): predictive factors for functional outcome. Study report no. 6. Graefes Arch Clin Exp Ophthalmol. 2011;249:1129–36.

    Article  Google Scholar 

  23. Baba T, Kawasaki R, Yamakiri K, Koto T, Nishitsuka K, Yamamoto S, et al. Visual outcomes after surgery for primary rhegmatogenous retinal detachment in era of microincision vitrectomy: Japan-Retinal Detachment Registry Report IV. Br J Ophthalmol. 2021;105:227–32.

    Article  PubMed  Google Scholar 

  24. Madgula IM, Costen M. Functional outcome and patient preferences following combined phaco-vitrectomy for macular hole without prone posturing. Eye. 2008;22:1050–3.

    Article  CAS  PubMed  Google Scholar 

  25. Yorston D, Siddiqui MAR, Awan MA, Walker S, Bunce C, Bainbridge JW. Pilot randomised controlled trial of face-down posturing following phacovitrectomy for macular hole. Eye. 2012;26:267–71.

  26. Fajgenbaum MAP, Neffendorf JE, Wong RS, Laidlaw DAH, Williamson TH. Intraoperative and postoperative complications in phacovitrectomy for epiretinal membrane and macular hole. Retina. 2018;38:1865–72.

    Article  PubMed  Google Scholar 

  27. Bellucci C, Romano A, Ramanzini F, Tedesco SA, Gandolfi S, Mora P. Pars Plana Vitrectomy Alone or Combined with Phacoemulsification to Treat Rhegmatogenous Retinal Detachment: A Systematic Review of the Recent Literature. J Clin Med. 2023;12:5021.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Radeck V, Helbig H, Maerker D, Gamulescu MA, Prahs P, Barth T. Rhegmatogenous retinal detachment repair—does age, sex, and lens status make a difference? Graefes Arch Clin Exp Ophthalmol. 2022;260:3197–204.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Moussa G, Sachdev A, Mohite AA, Hero M, Ch’ng SW, Andreatta W. Assessing refractive outcomes and accuracy of biometry in phacovitrectomy and sequential operations in patients with retinal detachment compared with routine cataract surgery. Retina. 2021;41:1605–11.

    Article  CAS  PubMed  Google Scholar 

  30. Radeck V, Helbig H, Barth T, Gamulescu MA, Prahs P, Maerker D. Ablatiochirurgie: Trends über 15 Jahre. Ophthalmol. 2022;119:64–70.

    Article  Google Scholar 

  31. Moussa G, Kalogeropoulos D, Wai Ch’ng S, Lett KS, Mitra A, Tyagi AK, et al. The Effect of Supervision and Out-of-Hours Surgery on the Outcomes of Primary Macula-On Retinal Detachments Operated by Vitreoretinal Fellows: A Review of 435 Surgeries. Ophthalmologica. 2022;245:239–48.

    Article  PubMed  Google Scholar 

  32. Teh BL, Al-Zubaidy M, Hillier RJ, Steel DH, Newcastle/Sunderland VR Study Group. Outcomes of weekend surgery for acute retinal detachment. Eye. 2023;37:1942–43.

    Article  PubMed  Google Scholar 

Download references

Funding

Funding for statistical analysis was provided by the Britain & Eire Association of Vitreoretinal Surgeons. The design and development of the database software was funded by Euretina.

Author information

Authors and Affiliations

Authors

Consortia

Contributions

DY - original conception, design of study, first draft of manuscript. PD - statistical analysis. DAHL - revision of manuscript, design of study, interpretation of data. DS - revision of manuscript, design of study, interpretation of data. TW - revision of manuscript, design of study, interpretation of data.

Corresponding author

Correspondence to David Yorston.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary information

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yorston, D., Donachie, P.H.J., Laidlaw, D.A. et al. Predicting post-surgery change in visual acuity after successful repair of macula-off retinal detachments: findings from a large prospective UK cohort study. Eye 39, 2298–2306 (2025). https://doi.org/10.1038/s41433-025-03752-y

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue date:

  • DOI: https://doi.org/10.1038/s41433-025-03752-y

This article is cited by

Search

Quick links