Fig. 1: Circulating alanine aminotransferase (ALT) and aspartate transaminase (AST) levels in a cohort of SMA patients treated at the pre-symptomatic stage with onasemnogene abeparvovec.
From: Early life safety profiling of gene therapy for spinal muscular atrophy

A–H Cohort receiving monotherapy. Blue line indicates the day of injection. Colored background area indicates normal concentrations expected in sex-matched controls.