Fig. 4

CsA administration inhibited the enhancement of inflammatory cytokine levels in eclampsia-like rats. The concentrations of TNF-α and IL-1β were significantly reduced in the PE + PTZ group treated with CsA. a Compared with those in the P + PTZ group, the IL-1β levels were significantly higher in the PE + PTZ group (*p < 0.01) but were lower in the PE + CsA + PTZ group compared with the PE + PTZ group (^#p < 0.01). b After PTZ stimulation, the TNF-α levels increased significantly in the PE group compared with that in the P group; following CsA administration (*p < 0.01), the levels were lower in the PE + CsA + PTZ group than the PE + PTZ group (^#p < 0.01). c The changing tendency of IL-17 levels was similar to that of TNF-α and IL-1β. d There was also no significant difference in IL-10 levels within each group after PTZ stimulation