Table 4 Factors possibly related to the counts of lacunes, microbleeds, and EVRS using generalized estimating equations

From: Home-measured orthostatic hypotension associated with cerebral small vessel disease in a community-based older population

 

Number of lacunes (counts)

Number of microbleeds (counts)

Number of EVRS (counts)

 

Beta coefficient (95% CI)

Wald χ2

P value

Beta coefficient (95% CI)

Wald χ2

P value

Beta coefficient (95% CI)

Wald χ2

P value

1 Episode of HOH

0.382 (0.019, 0.745)

5.317

0.022

0.483 (0.006, 0.959)

3.936

0.047

≥2 Episodes of HOH

1.584 (1.043, 2.125)

32.887

<0.001

0.798 (0.170, 1.426)

6.205

0.013

1.011 (0.473, 1.549)

13.575

<0.001

Home SBP (mmHg)

0.002 (0.000, 0.004)

4.153

0.041

0.002 (0.000, 0.004)

4.461

0.032

Age (years)

0.051 (0.009, 0.092)

5.803

0.016

0.042 (0.003, 0.082)

4.440

0.035

0.073 (0.035, 0.111)

14.313

<0.001

LDL-c (mmol/L)

0.540 (0.100, 0.979)

5.795

0.016

FPG (mmol/L)

0.095 (0.025, 0.165)

4.333

0.037

0.218 (0.013, 0.423)

4.819

0.029

Alcohol consumption

0.564 (0.056, 1.073)

4.733

0.030

Heart rate (bpm)

−0.036 (−0.069, −0.003)

4.558

0.033

Anti-diabetes medication

−25.634 (−26.451, −24.818)

3784.104

<0.001

Antihypertensive medication

−0.557 (−0.997, −0.117)

6.158

0.013

  1. EVRS enlarged Virchow–Robin spaces, CI confidence interval, HOH home-measured orthostatic hypotension, SBP systolic blood pressure, LDL-c low-density lipoprotein-cholesterol, FPG fasting plasma glucose