Table 1 Baseline patient characteristics for men ≥18 before and after propensity score matching.
Characteristic | Before Matching: Low Testosterone (N = 265,816) | Before Matching: Normal Testosterone (N = 530,406) | Before Matching: Standardized Mean Difference | After Matching: Low Testosterone (N = 263,557) | After Matching: Normal Testosterone (N = 263,557) | After Matching: Standardized Mean Difference |
|---|---|---|---|---|---|---|
Age at Index (Mean ± SD) | 53.4 ± 15.7 | 50.3 ± 15.2 | 0.20125 | 53.3 ± 15.7 | 52.9 ± 15.3 | 0.02315 |
Age at Index (18–24 years) | 11,750 | 29,052 | 0.04875 | 11,739 | 11648 | 0.00168 |
Age at Index (25–33 years) | 22,613 | 58,092 | 0.08258 | 22,594 | 22,582 | 0.00016 |
Age at Index (34–44 years) | 42,828 | 100,534 | 0.07480 | 42,750 | 42,956 | 0.00212 |
Age at Index (45–54 years) | 54,439 | 117,981 | 0.04304 | 54229 | 54,525 | 0.00278 |
Age at Index (55–64 years) | 62,080 | 121,469 | 0.01075 | 61,648 | 61,882 | 0.00210 |
Age at Index (>65 years) | 72,106 | 103,278 | 0.18182 | 70,597 | 69,964 | 0.00543 |
White | 188,820 | 380,605 | 0.01600 | 187,289 | 187,014 | 0.00230 |
Not Hispanic or Latino | 185,847 | 363,657 | 0.02933 | 183,950 | 183,751 | 0.00164 |
Black or African American | 32,678 | 57,199 | 0.04726 | 32,181 | 32178 | 0.00003 |
BMI (Mean ± SD) | 30.5 ± 6.2 | 28.6 ± 5.3 | 0.33901 | 30.3 ± 6.1 | 30.2 ± 5.9 | 0.02350 |
BMI ( < 18.5 kg/m2) | 1365 | 2180 | 0.01511 | 1324 | 1297 | 0.00146 |
BMI (18.5–24.9 kg/m2) | 12,273 | 33,456 | 0.07444 | 12,244 | 11,848 | 0.00719 |
BMI (25–29.9 kg/m2) | 25,228 | 57,823 | 0.04664 | 25,115 | 24,947 | 0.00217 |
BMI (30–34.9 kg/m2) | 20701 | 33,089 | 0.06070 | 20,259 | 20,716 | 0.00648 |
BMI (35–39.9 kg/m2) | 10570 | 12,063 | 0.09794 | 9807 | 10,144 | 0.00670 |
BMI ( > 40 kg/m2) | 5985 | 5158 | 0.10170 | 5209 | 5039 | 0.00467 |
Essential hypertension | 59950 | 33,089 | 0.12514 | 58,238 | 59,019 | 0.00713 |
Diabetes mellitus | 30880 | 93,100 | 0.14368 | 29,427 | 29,907 | 0.00576 |
Coronary artery disease | 13527 | 18,357 | 0.08054 | 12,802 | 12,762 | 0.00071 |
Chronic kidney disease | 10220 | 12,181 | 0.08983 | 9469 | 9511 | 0.00086 |
Heart failure | 6361 | 6469 | 0.08819 | 5649 | 5475 | 0.00459 |
Gout | 4797 | 6243 | 0.05181 | 4514 | 4548 | 0.00099 |
Cerebral infarction | 2129 | 2730 | 0.03541 | 2002 | 1967 | 0.00154 |
Acute myocardial infarction | 1811 | 2081 | 0.03955 | 1659 | 1543 | 0.00566 |
Pulmonary embolism | 1674 | 1830 | 0.04089 | 1523 | 1451 | 0.00365 |
Acute deep vein thrombosis | 1575 | 1720 | 0.03972 | 1424 | 1380 | 0.00230 |
Hyperparathyroidism and other disorders of parathyroid gland | 668 | 1124 | 0.00819 | 646 | 648 | 0.00015 |
Crohn’s disease | 643 | 1400 | 0.00439 | 637 | 617 | 0.00156 |
Bariatric surgery status | 401 | 978 | 0.00820 | 398 | 382 | 0.00158 |
Family history of disorders of kidney and ureter | 62 | 84 | 0.00535 | 57 | 52 | 0.00132 |
Hydrochlorothiazide | 14707 | 21,789 | 0.06655 | 14,259 | 14,450 | 0.00319 |
Furosemide | 9589 | 9124 | 0.11740 | 8505 | 8254 | 0.00543 |
Chlorthalidone | 1542 | 2140 | 0.02525 | 1474 | 1466 | 0.00041 |
Topiramate | 926 | 1582 | 0.00883 | 903 | 895 | 0.00052 |
Acetazolamide | 387 | 489 | 0.01550 | 357 | 311 | 0.00491 |