Table 1 Quantification of open discs and OS diameter for P15 and PI-45 Prph2Y141C/+ mRho ASO treated and their corresponding untreated contralateral control eyes

From: Downregulation of rhodopsin is an effective therapeutic strategy in ameliorating peripherin-2-associated inherited retinal disorders

Samples

Number of Open Discs (mean ± SD)

OS Diameter (µm) (mean ± SD)

P15 Prph2Y141C/+ injected mice with mRho ASO1

P15 Contralateral Control One

12.0 ± 0.6

1.80 ± 0.06

P15 Treated Sample One

6.8 ± 0.4

1.29 ± 0.04

P15 Contralateral Control Two

12.8 ± 0.9

1.79 ± 0.05

P15 Treated Sample Two

7.4 ± 0.4

1.29 ± 0.03

P45 Prph2Y141C/+ injected mice with mRho ASO1

P45 Contralateral Control One

11.7 ± 0.6

2.00 ± 0.08

P45 Treated Sample One

7.4 ± 0.5

1.35 ± 0.04

P45 Contralateral Control Two

12.0 ± 0.9

1.97 ± 0.06

P45 Treated Sample Two

7.7 ± 0.5

1.21 ± 0.05

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