Fig. 7: Structural comparison of GPCRs with N-terminal regions.

a–e Structural comparison of the N-terminal region in PTH1R (PDB 7VVK(PTH-PTH1R–G_s structure)) (a), TSHR (PDB 7XW5 (ML109–TSHR–G_s structure)) (b), CXCR2 (PDB 8XWN (CXCL8–CXCR2 structure)) (c), C5aR (PDB 8HK5 (C5a–C5aR1–G_i structure)) (d), and GPR103 (e).