Fig. 3: Cryo-EM structure of pN162 bound MC4R-Gs-Cb35 complex.
From: Structure elucidation of a human melanocortin-4 receptor specific orthosteric nanobody agonist
a Cryo-EM density map (sharpened with DeepEMhancer, 8QJ2, and EMD_18442). b Final model submitted to the Protein Data Bank (PDB ID 8QJ2). The color code for the proteins is light blue for pN162, purple for MC4R, salmon pink for DNGαs (Gαs), light green for Gβ, orange for Gγ, and magenta for Cb35.
