Fig. 2: Effects of unidirectional blockade of the interhemispheric pathway on recovered hand movements.
From: Stage-dependent role of interhemispheric pathway for motor recovery in primates
A Success rate of precision grip before (open circles) and after (red circles) DCZ administration and after vehicle administration (blue circles). The dotted lines indicate the days when the results of the reaching and grasping times shown in (C) were obtained. *P < 0.05 (two-sided Pearson’s χ2 test; Monkey A: P = 3.0 × 10–7 [day 45], 0.0071 [day 49]; Monkey H: P = 1.2 × 10−4 [day 31], 6.4 × 10–7 [day 35], 0.028 [day 36], 0.017 [day 38]). B Examples of food retrieval behavior before (upper figures) and after (lower figures) DCZ injection; 45 days after lesioning in Monkey (A). C Grasping and reaching time before (white bars) and after (red bars) DCZ administration; 45 days after lesioning in Monkey A (Pre-DCZ: 70 trials, Post-DCZ: 56 trials), and 35 days after lesioning in Monkey H (Pre-DCZ: 70 trials, Post-DCZ: 69 trials). Data are presented as mean values ± SD. *P < 0.05 (two-sided Wilcoxon rank-sum test; Grasping time: P = 5.1 × 10–6 [Monkey A], 1.3 × 10−11 [Monkey H]; reaching time: P = 8.3 × 10−5 [Monkey A], 7.3 × 10−4 [Monkey H]).
