Table 6 Cox regression analyses for predictors of systemic embolism events in patients with LVA and without clear indication for anticoagulation

From: Clinical characteristics and prognostic importance of anticoagulant use in ischemic left ventricular aneurysm: a retrospective cohort study

 

Univariate analysis

Multivariable analysis*

 

SHR (95% CI)

P-value

SHR (95% CI)

P-value

Age

1.03 (1.01−1.05)

0.013

  

Male

1.13 (0.60−2.13)

0.714

  

BMI

0.96 (0.88−1.04)

0.293

  

Smoking

1.30 (0.73−2.30)

0.372

  

Drinking

0.91 (0.39−2.13)

0.834

  

Hypertension

3.15 (1.66−5.99)

0.001

  

Diabetes mellitus

1.93 (1.11−3.37)

0.021

  

Prior stroke/TIA

9.59 (5.28−17.43)

<0.001

9.05 (5.09−16.11)

<0.001

Anticoagulant agent

0.10 (0.01−0.76)

0.026

0.13 (0.02−0.97)

0.046

Akinesis in apical segments

1.89 (1.08−3.31)

0.026

1.90 (1.07−3.35)

0.028

Years of inclusion

1.09 (0.99−1.20)

0.090

  
  1. All statistical tests were two-sided at a significance level of 0.05.
  2. LVA left ventricular aneurysm, CI confidence interval, SHR subdistribution hazard ratio, BMI body mass index, TIA transient ischemic attack.
  3. *Nonsignificant variables were eliminated after the multivariable model run, including age, male, BMI, hypertension, diabetes mellitus, smoking, drinking and years of inclusion.
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