Fig. 4: Results of the α-alkylation of nitriles with alcohols.
From: Enable biomass-derived alcohols mediated alkylation and transfer hydrogenation
Reaction conditions: aromatic alcohols (0.55 mmol), nitriles (0.5 mmol), hexane (10 mL), the Zn–N4–C catalyst (20 mg), NaNH2 (1 equiv.), N2 (10 bar) and 160 °C; b These reactions are performed at 180 °C; c These reactions are performed at 200 °C. Note: Aliphatic alcohols are also used as the solvents; The yields in Fig. 4 are the isolated yields; The “Pro. x” represents “Product x”, and “x” is the number of the compound synthesized in this manuscript. The red part represents that it derives from alcohol.
