Fig. 8: Working model showing the intersection of the Hippo pathway and multiple stages of the EBOV lifecycle. | Nature Communications

Fig. 8: Working model showing the intersection of the Hippo pathway and multiple stages of the EBOV lifecycle.

From: Hippo signaling pathway regulates Ebola virus transcription and egress

Fig. 8

a Target genes of YAP/TAZ regulate the composition and function of the ECM/PM. b LATS1/2 kinases interact with NP and phosphorylate VP30 to regulate EBOV transcription. c Involvement of LATS1/2, YAP/TAZ, as well as AMOT in regulating EBOV/MARV egress.

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