Fig. 1: Initial conformation of the peptides and alamethicin aggregation.
From: Melittin can permeabilize membranes via large transient pores
a Single alamethicin adsorption and insertion. Side-view of the single peptide trajectories and peptide center of mass insertion (membrane = gray bar; red dotted line = membrane center; blue dotted lines = interfacial center-of-mass location of the peptides; membrane interface phase = light blue shading, trans-membrane inserted phase = light red shading). b Single melittin adsorption. c Alamethicin aggregation. The initial state is a 4×4 grid of the final snapshot of the single peptide simulation. d Oligomerization state (S = surface, yellow-black: increasing transmembrane oligomer size). e Membrane water number density.
