Fig. 3: Structures of Mutant IDH1 inhibitors 1–4.
From: Biostructural, biochemical and biophysical studies of mutant IDH1

Compound 1, identified from high-throughput screening, was evolved into more potent analogs 2-3 and an NMR tool compound 4.
From: Biostructural, biochemical and biophysical studies of mutant IDH1
Compound 1, identified from high-throughput screening, was evolved into more potent analogs 2-3 and an NMR tool compound 4.