Fig. 3: Retinal binding site of exoKCR1 and endoKCR1.
From: Channelrhodopsins with distinct chromophores and binding patterns

a The Schiff-base linked ATR in the retinal binding pocket model of exoKCR1 was present by Coot. The density is shown as purple mesh. Exogenous ATR is covalently linked to the conserved K233 via a canonical Schiff base. b Endo-retinal in the canonical retinal binding pocket models of endoKCR. The endo-retinal density (red box region) is not well fitted including the β-ionone ring and the polyene chain. c The retinal binding pocket models of exoKCR1 and endoKCR1 were present as cartoon. The distance between the retinal and Y103 is labeled. Y103 rotated around 70 degrees from exoKCR1 to endoKCR1 in coordination with the slight motion of the retinal.