Table 2 Treatment-related adverse events during and up to 6 months after treatmenta

From: Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study

 

All grades (n (%))

Grade 3 or 4 (n (%))

Constitutional

 Fatigue

6 (60)

0 (0)

 Chills

2 (20)

0 (0)

 Fever

2 (20)

0 (0)

Dermatologic

 Pruritis

2 (20)

0 (0)

Endocrine

 Hypothyroidism

2 (20)

0 (0)

Gastrointestinal

 Abdominal discomfort

3 (30)

0 (0)

 Diarrhoea

2 (20)

0 (0)

Genital tract

 Vaginal bleeding

3 (30)

0 (0)

Musculoskeletal

 Myalgia

4 (40)

0 (0)

 Arthralgia / joint stiffness

4 (40)

0 (0)

 Lower backpain

2 (20)

0 (0)

Neurologic

 Headache

3 (30)

0 (0)

Respiratory

 Cough

2 (20)

0 (0)

 Dyspnoea

2 (20)

0 (0)

  1. a Treatment-related adverse events that were present in at least 20% of patients at any grade and treatment-related adverse events of clinical interest.